Publications
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Balasubramanian R, Saha D, Arun A and Vinod PK*, Hypometabolism in Autism Spectrum Disorder: Insights from Brain and Blood Transcriptomics, 2024 (submitted).
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Jose A, Srivastava A and Vinod PK*, DeepGraphMut: A graph-based deep learning method for cancer prognosis using omics data, 2024 (submitted).
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Srivastava A and Vinod PK*, A single-cell network approach to decode metabolic regulation in Gynecologic and Breast Cancers, 2024 (under revision).
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Paranjape PS, Vinod PK, Vaidya T, Meta-analysis of the pathogen Leishmania donovani transcriptome reveals multiple modes of regulation including two reciprocally regulated gene modules, https://www.biorxiv.org/content/10.1101/2024.04.26.591251v1.full, 2024.
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Chauhan E, Sharma A, Uppin MS, Jawahar CV and Vinod PK*, Multiple Instance Learning for Glioma Diagnosis using Hematoxylin and Eosin Whole Slide Images: An Indian Cohort Study, https://arxiv.org/abs/2402.15832v2, 2024 (under revision).
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Sharma A, Chauhan E, Uppin MS, Rajasekhar L, Jawahar CV and Vinod PK*, Lupus nephritis subtype classfication with only slide-level labels, Proceedings of Machine Learning Research 1–10, Medical Imaging with Deep Learning (MIDL), Paris, https://openreview.net/forum?id=c1AfNZoSyQ, 2024.
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Porukala M and Vinod PK*, Gene expression signatures of stepwise progression of Hepatocellular Carcinoma, PLOS One, 18 (12), e0296454, 2023.
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Talwar V, Singh P, Mukhia N, Shetty A, Birur P, Desai K M, Sunkavalli C, Varma KS, Sethuraman R, Jawahar CV and Vinod PK*, AI-assisted screening of oral potentially malignant disorders using
smartphone-based photographic images, Cancers, 15 (16), 4120, 2023.
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Shetty KS, Jose A, Bani M and Vinod PK*, Network diffusion-based approach for survival prediction and identification of biomarkers using multi-omics data of Papillary Renal Cell Carcinoma, Molecular Genetics and Genomics, 298(4):871-882, 2023.
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Porukala M and Vinod PK*, Network-level analysis of ageing and its relationship with diseases and tissue regeneration in the mouse liver, NPG Scientific Reports, 13: 4632, 2023.
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Srivastava A and Vinod PK*, Identification and characterization of metabolic subtypes of endometrial cancer using a systems-level approach, Metabolites, 13(3), 409, 2023.
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Borkar K, Chaturvedi A, Priyakumar UD* and Vinod PK*, PREHOST: Host Prediction of Coronaviridae Family Using Machine Learning, Heliyon, 9(2):e13646, 2023.
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Balasubramanian R and Vinod PK*, Inferring miRNA sponge modules across major neuropsychiatric disorders, Frontiers In Molecular Neuroscience, 15: 10096622022, 2022.
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Ramya G, Mitra A* and Vinod PK*, Predicting functional riboSNitches in the context of alternative splicing, Gene, 837, 146694, 2022.
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Das A, Bapi RS, Roy D and Vinod PK, Characterizing dynamic reorganization in healthy ageing, International Joint Conference on Neural Networks (IJCNN),1-7, 2022
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Chandra K, Khare Y, Dadi K, Vinod PK* and Bapi RS*, Deep Learning approach for classification and interpretation of Autism Spectrum Disorder, International Joint Conference on Neural Networks (IJCNN), 1-8, 2022.
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Borkar K, Chaturvedi A, Vinod PK* and Bapi RS*, Ayu -Characterization of Healthy Aging from Neuroimaging Data with Deep Learning and rsfMRI, Frontiers in Computational Neuroscience, 16: 940922, 2022.
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Chauhan R, Jawahar CV and Vinod PK*, Bytes, Pixels, & Bases: Machine Learning in Imaging-omics for Renal Cell Carcinoma, Artificial Intelligence in Cancer Diagnosis andPrognosis, Volume 1, 2022 (IOP Publishing).
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Nishtha P, Vinod PK*, Model scenarios for cell cycle re-entry in Alzheimer's disease, iScience (cell press), 25(7):104543, 2022.
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Porukala M, Vinod PK*, Modeling of temporal reorganization of transcriptome during liver regeneration, Molecular Omics (Royal Society of Chemsitry), 18, 315-327, 2022.
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Menon A, Piyush Singh P, Vinod PK* and Jawahar CV*, Exploring histological similarities across cancers from a deep learning perspective, Frontiers in Oncology, 12:842759, 2022.
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Alle, S.; Garg, A.; Karthikeyan, A…. Sethuraman, R.; Subramanian, C.; Srivastava, M.; Chakravarthi, A.; Jacob, J.; Namagiri, M.; Konala, V.;… Vinod PK* and Priyakumar UD*, COVID-19 Risk Stratification and Mortality Prediction in Hospitalized Indian Patients: harnessing clinical data for public health benefits, PLOS One, 17(3):e0264785, 2022.
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Menon A, Piyush Singh P, Vinod PK and Jawahar CV, Interactive Learning for Assisting Whole Slide Image Annotation, ACPR 2021: Pattern Recognition pp 504–517A, 2022.
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Bagal V, Aggarwal R, Vinod PK and Priyakumar UD*, MolGPT: Molecular Generation Using a Transformer-Decoder Model, J. Chem. Inf. Model, 62, 9, 2064–2076, 2021.
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Mehta P, Alle S, Chaturvedi A... Priyakumar UD*, Vinod PK* and Pandey R*, Clinico-Genomic analysis reveals mutations associated with COVID-19 disease severity: possible modulation by RNA structure, 10(9), 1109, Pathogens, 2021.
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Moolamalaa STR, Balasubramanian R, Chauhan R, Priyakumar UD and Vinod PK*, Host metabolic reprogramming in response to SARS-Cov-2: A Systems Biology approach, Microb Pathog, 158:105114, 2021.
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Karthikeyan A, Garg A, Vinod PK* and Priyakumar UD*, Machine learning based clinical decision support system for early COVID-19 mortality prediction, Front Public Health,12;9:626697, 2021.
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Chauhan R, Vinod PK* and Jawahar CV*, Exploring genetic-histologic relationships in breast cancer, IEEE International Symposium on Biomedical Imaging (ISBI) 2021.
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Moolamalaa STR and Vinod PK*, Genome-scale metabolic network reconstruction and analysis of neuropsychiatric disorders, Comput. Biol. Med, 125, 103994, 2020.
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Dangarh P, Pandey N and Vinod PK*, Modeling the control of meiotic cell divisions: Entry, Progression and Exit, Biophysical Journal, 119,5,1015-1024, 2020.
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Pandey N, Lanke V, Vinod PK*, Network-based metabolic characterization of renal cell carcinoma, NPG Scientific Reports, 10, 5955, 2020.
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Noor P S, Vinod PK*, Integrative analysis of DNA methylation and gene expression in Papillary Renal Cell Carcinoma, Molecular Genetics and Genomics,295, 807–824, 2020.
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Kapuy O, Márton M, Bánhegyi G, and Vinod PK, Multiple system-level feedback loops control life-and-death decision in endoplasmic reticulum stress, FEBS Lett., doi: 10.1002/1873-3468.13689.2019.
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Tabibu S, Vinod PK* and Jawahar CV*, Pan-Renal Cell Carcinoma classification and survival prediction from histopathology images using deep learning, NPG Scientific Reports, 9, 10509, 2019.
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Vatika H, Bapi R S, Vinod PK* and Roy D*, Atypical flexibility in dynamic functional connectivity quantifies the severity in autism spectrum disorder, Front. Hum. Neurosci., 13(6), 2019.
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Shubham K and Vinod PK*, Single-cell transcriptomic analysis of Pancreatic Islets in Health and Type 2 Diabetes, Int J Adv Eng Sci Appl Math, special issue on Algorithms for Network Biology (springer),11(2),105-118, 2019.
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Vatika H, Bapi R S, Vinod PK* and Roy D*, Age, disease and their interaction effects on intrinsic connectivity of children and adolescents in Autism Spectrum Disorder using functional connectomics, Brain Connectivity, 8(7), 2018.
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Noor P S, Bapi R S, and Vinod PK*, Machine learning models to predict the progression from early to late stages of papillary renal cell carcinoma, Comput. Biol. Med, 1;100:92-99, 2018.
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Pandey N and Vinod PK*, Mathematical modelling of reversible transition between quiescence and proliferation, PLoS ONE, 13(6): e0198420, 2018.
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Lanke V, Moolamalla S T R, Roy D and Vinod PK*, Integrative analysis of hippocampus gene expression profiles identifies network alterations in ageing and Alzheimer’s disease, Front. Aging Neurosci., 10:153, 2018.
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Kapuy O, Bánhegyi G, Vinod PK and Novak B, Systems-level feedback regulation of cell cycle transitions in Ostreococcus tauri, Plant Physiology and Biochemistry,126:39-46, 2018.
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Bhola T, Kapuy O, Vinod PK*, Computational modeling of meiotic entry and commitment, NPG Nature Scientific Reports, 8:180, 2018.
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Shubham K, Vinay L, Vinod PK*, Systems-level organization of non-alcoholic fatty liver disease progression network, Mol Biosyst., 3(9):1898-1911, 2017.
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Vinod PK, Novák B, Model scenarios for switch-like mitotic transitions, FEBS Lett., 589(6),667-671(2015).
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Kapuy O, Vinod PK, Mandl J, Banhegyi G, mTOR inhibition increases cell viability via autophagy induction during endoplasmic reticulum stress – An experimental and modeling study, FEBS Open Bio., 4, 704-713 (2014).
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Rattani A, Vinod PK, Godwin J, Tachibana-Konwalski K, Wolna M, Malumbres M, Novák B and Nasmyth K, Dependency of the spindle assembly checkpoint on Cdk1 renders the anaphase transition irreversible, Curr. Biol., 24, 1-8 (2014).
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Hegarat N*, Vesely C*, Vinod PK, Occasio C, Oliver A, Novák B and Hochegger H, PP2A/B55 and Fcp1 regulate Greatwall and ENSA dephosphorylation during mitotic exit, PLoS Genet.,10(1), e004004 (2014) (*equal contribution).
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Vinod PK, Zhou X, Zhang T, Mayer TU and Novák B, The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles, Biophys. Chem., 177, 1-6 (2013).
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Verdugo A*, Vinod PK*, Tyson JJ, Novák B, Molecular mechanisms creating bistable switches at cell cycle checkpoints, Open Biol., 3(3), 120179(2013) (*equal contribution).
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Vinod PK, Novák B, Cell cycle transitions, mitotic exit, Encyclopedia of Systems Biology, Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota (Eds.), Springer, (2013).
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Kapuy O, Vinod PK, Mandl J, Banhegyi G, A cellular stress-directed bistable switch controls the crosstalk between autophagy and apoptosis, Mol. Biosyst., 9(2), 296-306 (2013).
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Okaz E, Arguello MO, Bogdanova A, Vinod PK, Lipp JJ, Markova Z, Rybak I, Novák B, Zachariae W, Meiotic prophase requires proteolysis of M-phase regulators mediated by APC/C, Cell, 151(3): 603-18 (2012).
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Freire P, Vinod PK, Novák B, Interplay of transcriptional and proteolytic regulation in driving robust cell cycle progression, Mol. Biosyst., 8(3), 863-70(2012).
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Vinod PK, Freire P, Ahmed R, Ciliberto A, Uhlmann F, Novák B, Computational modeling of mitotic exit in budding yeast- the role of separase and Cdc14 endocycles, J. R. Soc. Interface, 8(61):1128-41(2011).
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Novák B, Vinod PK, Freire P, Kapuy O, Systems-level feedback in cell-cycle control, Biochem. Soc. Trans., 38(5):1242-6(2010).
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Vinod PK, Venkatesh KV, Quantification of the effect of amino acids on an integrated mTOR and insulin signaling pathway, Mol. Biosyst., 5(10):1163-73(2009).
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Vinod PK, Venkatesh KV, A steady state model for the transcriptional regulation of filamentous growth in Saccharomyces cerevisiae, In Silico Biol., 8(3-4):207-22(2008).
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Vinod PK, Sengupta N, Bhat PJ, Venkatesh KV, Integration of global signaling pathways, cAMP-PKA, MAPK and TOR in the regulation of FLO11, PLoS One. 3(2):e1663 (2008).
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Vinod PK, Venkatesh KV, Quantification of biological signaling and regulatory networks, J. IISc, 88:1(2008) (National).
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Vinod PK, Venkatesh KV, Specificity of MAPK signalling towards FLO11 expression is established by crosstalk from cAMP pathway, Syst. Synth. Biol., 1(2):99-108(2007).
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Sengupta N*, Vinod PK*, Venkatesh KV, Crosstalk between cAMP-PKA and MAP kinase pathways is a key regulatory design necessary to regulate FLO11 expression, Biophys. Chem., 125(1):59-71(2007) (*equal contribution).
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Vinod PK, Venkatesh KV, Steady state analysis to study signaling specificity involved in the regulation of FLO11 regulation, Foundations of Systems Biology in Engineering (FOSBE proceedings), Stuttgart, Germany (2007).
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Vinod PK, Konkimalla B, Chandra N, In-silico pharmacodynamics: correlation of adverse effects of H2-antihistamines with histamine N-methyl transferase binding potential, Appl Bioinformatics, 5(3):141-50(2006).
Conferences/Presentations (from IIIT)
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Moolamalla STN, Vinod PK*, Metabolic Network Modelling of Neuro-Psychiatric Disorders, 20th International Conference on Systems biology (ICSB2019), Okinawa, Japan, November, 2019.
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Dangarh P, Pandey N, Vinod PK*, Systems-level modeling of meiosis regulatory network, 20th International Conference on Systems biology (ICSB2019), Okinawa, Japan, November, 2019.
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Vinod PK*, Network and trajectory inference approaches to understand the behavior of pancreatic cells in healthy and Type 2 diabetes, Mathematical and statistical explorations in disease modelling and public health, ICTS, Bangalore, 2019.
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Kapuy O, Holczer1 M, Márton M, Besze B, Hajdú B, Vinod PK* and Bánhegyi G, A Systems Biological Analysis of Cellular Life-and-death Decision in Neurodegenerative Diseases, FEBS3+ conference ‘From molecules to living systems’, Siófok, Hungary, 2018.
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Noor P S, Bapi R S, and Vinod PK*, Identification of Biomarkers for Cancer Stage Progression, NGBT Conference, Bhubaneswar, 2017.
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Vinod PK, Integrative modelling of adipose tissue inflammation in non-alcoholic fatty liver disease, Indo-European Meeting on Mathematical Models of Infection, Inflammation and Immunity, IISc Bangalore, April 2017.
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Shubham K, Vinay L, Vinod PK, Systems-level organization of fatty liver disease network, The fifteenth theoretical chemistry symposium (TCS), Hyderabad, 2016.
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Tanvi Bhola, Vinod PK, Mathematical modelling of mitosis to meiosis transition, NNMCB National Meeting, Pune, 2015.
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Vatika Harlalka, Vinod PK, Dipanjan R, Relationship between regional firing rate and resting-state functional connectivity in the cortex - A computational study, 3rd International Conference on Cognition, Brain and Computation, IIT Gandhinagar, 2015.