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Research interests: Computational Biology and Computational Physics

 

Complex Dynamical Systems Analysis

o   Analysis of Dynamical networks: characterization, synchronization and control of spatiotemporal dynamics on different topological networks with applications to biological systems

o   Air-transport networks with applications to infectious disease transmission

 

Systems Biology: Graph-based Analysis of Biological Networks

o   Analysis of Protein Contact Networks

- Identifying tandem structural repeats

- Domain identification

- Identifying critical residues

o   Analysis of Metabolic networks

 

Protein Sequence Analysis: Pattern recognition, Developing Algorithms and Specialized Databases:

o   Identifying Peptide Periodic Repeats in Protein Sequences

o   Web-based Tool: PEPPER http://bioinf.iiit.net/PEPPER/

o   Web-based Database: DRiPS http://bioinf.iiit.ac.in/PEPPER/PTRDB_new/

o   Computation analysis of protein conformational changes

 

Genome Analysis: Pattern recognition, Comparative genomics, Data mining, Developing Algorithms and Specialized Databases:

o   An Integrated Data Mining Tool for Function Analysis of SNPs: ComPreSNPdb (In collaboration with CCMB, Hyderabad)

o   Identifying Genomic Islands and Pathogenicity Islands (IGIPT): http://bioinf.iiit.ac.in/IGIPT/

o   Development of Comprehensive Gene Database - CHGD (In collaboration with CCMB, Hyderabad)

 

Funded Projects:

Identification of Critical Residues in Protein Folds Using Graph Theoretic Approaches - PI

(Sanctioned by: CSIR, India, April 2011)

Computational Core for Plant Metabolomics - one of the Co-PI from IIIT

(Sanctioned by: DBT, India, Oct 2011)

Pathosystems Biology-Computational Analysis of Rice-Pathogen Interaction Networks - Co-Investigator from IIIT

(Submitted to: ICAR, India, April 2011)

Identification and analysis of protein folds using graph theoretic approaches - one of the PIs

(Submitted to DST)

Analysis of protein contact networks: Implications for protein stability - one of the PIs

(Sanctioned by: IBM, January 2009 - 2011)